NCT05349916

The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Purdue University · Academic / Other
• Sex: All
• Age: 22 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The main objective of the current study is to investigate whether consumption of soluble fibers (isomaltodextrin \[IMD\], partially digestible maltodextrin) and RS4 starch will lower postprandial glycemia as well as postprandial insulin in human subjects with relatively high fasting blood glucose, when consumed with a specific amount of digestible carbohydrate (rice porridge). The primary outcome of the study is the effect of fibers on postprandial blood glucose, whereas the secondary outcome will be its effect on postprandial blood insulin.

Conditions

• Postprandial Hyperglycemia
• Type2 Diabetes
• Blood Sugar; High

Interventions

Type	Name	Description
OTHER	Control	300 g rice porridge + 150 ml drinking water
OTHER	Isomaltodextrin Low Dose	300 g rice porridge + (5 g IMD in 150 ml drinking water)
OTHER	Isomaltodextrin High Dose	300 g rice porridge + (10 g IMD in 150 ml drinking water)
OTHER	GPC partially digestible maltodextrin	300 g rice porridge + (15 g GPC fiber in 150 ml drinking water)
OTHER	Resistant Starch Type 4	300 g rice porridge + (15 g RS4 starch in 150 ml drinking water)

Timeline

• Start date: 2021-12-07
• Primary completion: 2022-03-09
• Completion: 2022-03-09
• First posted: 2022-04-27
• Last updated: 2022-04-27

Locations

1 site across 1 country: United States