Clinical Trials Directory

Trials / Unknown

UnknownNCT05349409

A Trial of the Combination of SHR-A1811 and Fluzoparib in HER2-Expressing Cancers

A Phase Ⅰb/Ⅱ Clinical Study on the Dosage Exploration and Efficiency Expansion of SHR-A1811 for Injection in Combination With Fluzoparib Capsule in HER2-Expressing Advanced Solid Tumors of Patients

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
212 (estimated)
Sponsor
Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study is being conducted to evaluate safety, tolerability and preliminary efficacy of SHR-A1811 for Injection in combination with Fluzoparib Capsule for HER2-expressing advanced solid tumors of patients. To explore the reasonable dosage of dosage regimen of combination therapy for HER2-expressing advanced malignant tumors of patients.

Conditions

Interventions

TypeNameDescription
DRUGSHR-A1811SHR-A1811 for Injection: Given IV.
DRUGFluzoparib CapsuleFluzoparib Capsule: Given PO.

Timeline

Start date
2022-06-09
Primary completion
2024-11-30
Completion
2025-05-31
First posted
2022-04-27
Last updated
2022-06-30

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT05349409. Inclusion in this directory is not an endorsement.