NCT05343247

Dental Age Estimation by Different Methods in Patients With Amelogenesis Imperfecta

Evaluation of Dental Age of Children With Amelogenesis Imperfecta Using Cameriere European Formula and London Atlas

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 416 (actual)
• Sponsor: Istanbul University · Academic / Other
• Sex: All
• Age: 5 Years – 13 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to investigate whether there is a significant difference in dental age between children with amelogenesis imperfecta (AI) and healthy controls using Cameriere European formula and London Atlas. If there is a significant difference in dental age between children with AI and healthy controls, it is aimed to create a new formula.

Detailed description

One of the developmental enamel defects, amelogenesis imperfecta (AI), is also known as enamel hypoplasia/hypomineralization. It is a rare inherited disease that affects the enamel structure, amount and component in primary and permanent teeth, and it has been reported to be accompanied by some dental anomalies and nephrocalcinosis. Dental anomalies and nephrocalcinosis can affect tooth development, and there are limited studies examining tooth development in these individuals.Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan. Dental age is widely evaluated by pedodontists, forensic dentists and orthodontists. While a delay in tooth development may be associated with growth retardation and learning difficulties, dental age determination can also be used for forensic age determination for children whose birth information is uncertain. A clear assessment of maturation in children with continued growth is important in establishing a dental treatment plan. There are two basic approaches to dental age determination in children: 1. evaluation of eruption of teeth in the oral cavity, 2. evaluation of the development and mineralization of crowns and roots on dental radiographs. In many methods, the developmental stages of different numbers of permanent teeth are used. One of the most widely used methods of dental age determination recently is the European formula of Cameriere et al., which is calculated based on open apex. It has been reported that this method has been tested on different population groups, and the results are accurate and reliable. An atlas method was proposed by a group of London researchers in 2010. The Atlas shows all the teeth array images of certain age groups as a schematic series. Age determination is made by deciding which reference image matches the individual's panoramic radiography image more.

Conditions

• Amelogenesis Imperfecta
• Dental Age Estimation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cameriere method	Cameriere et al. designed a quantitative approach through a formula based on sex and the ratio between length and apex opening measurements of each lower left tooth.
DIAGNOSTIC_TEST	London Atlas method	The London Atlas requires the user to assess the tooth development and eruption and then match it to one of the 31 pictures of age categories.

Timeline

• Start date: 2022-03-01
• Primary completion: 2024-04-15
• Completion: 2024-04-23
• First posted: 2022-04-25
• Last updated: 2024-08-22

Locations

1 site across 1 country: Turkey (Türkiye)