NCT05342766

Precision Nutrition

Nutritia de Precizie

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 46 (actual)
• Sponsor: Shape Divine Center SRL · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Determine the relationship between relevant genotypes and nutrient plasma levels, with the aim to normalize such levels using a nutritional intervention. (Original text in Romanian language: Caracterizarea precisa a relatiei dintre variatiile genetice si nivelul de nutrienti din sange/plasma/ser, in scopul de a defini modul in care aportul alimentar poate normaliza aceste nivele.)

Detailed description

1. Define plasma levels prediction formulas for each involved nutrient, based on relevant genotypes; 2. Characterize the roles that food intakes may have in the alteriations of such plasma levels, depending on genotype structure; 3. Based on clinical data, create predictive equations using dependent variables (genotypes) in order to define optima nutrient intakes; 4. (Secondary aim): compare the efficacy of a nutrigenetic-based intervention with a non-nutrigenetic intervention (classical approach). (Original text in Romanian language: 1. Definirea unor formule de predictie a nivelelor din sange, in functie de variatiile genetice; 2. Caracterizarea rolului pe care aportul alimentar de nutrienti il are in modularea acestor valori, in contextul variatiilor genetice. 3. Gasirea unor formule de predictie in care variabilele independente (variatii genetice si combinatii ale acestora) sa defineasca necesarul de nutrienti pentru a normaliza valorile sangvine ale acestor nutrienti. 4. (Obiectiv secundar): compararea eficacitatii unei interventii nutrigenetice fata de o interventie clasica nutritionala (non-nutrigenetica).)

Conditions

• Nutrient Deficiency

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Nutrigenetic	Each grup will receive two interventions ("Nutrigenetic" and "Standard"), in a cross-over design (3 months each), spaced by a wash-out period (3 months).

Timeline

• Start date: 2022-05-01
• Primary completion: 2023-01-31
• Completion: 2023-10-01
• First posted: 2022-04-25
• Last updated: 2025-05-15

Locations

1 site across 1 country: Romania