Trials / Recruiting
RecruitingNCT05341492
EGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer
A Single-arm, Open, Exploratory Clinical Study Evaluating the Safety and Efficacy of EGFR/B7H3 CAR-T in Patients With EGFR/ B7H3-positive Advanced Solid Tumors (Lung and Triple-negative Breast Cancer)
- Status
- Recruiting
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
This study is a single-arm, open, exploratory clinical study to evaluate the safety and efficacy of EGFR/B7H3 CAR-T in patients with EGFR/ B7H3-positive advanced solid tumors (lung cancer and triple-negative breast cancer)
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | EGFR/B7H3 CAR-T | 2 × 10\^6/kg CAR-T cells,For subjects with body weight greater than 60 kg, the number of cells can only be calculated according to 60 kg of body weight. |
Timeline
- Start date
- 2022-05-01
- Primary completion
- 2030-05-01
- Completion
- 2035-05-01
- First posted
- 2022-04-22
- Last updated
- 2024-06-25
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT05341492. Inclusion in this directory is not an endorsement.