NCT05340010

Administration of Human Chorionic Gonadotrophin Before Secretory Transformation of Frozen-thawed Embryo Transfer Cycles

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 180 (actual)
• Sponsor: Alexandria University · Academic / Other
• Sex: Female
• Age: 18 Years – 38 Years
• Healthy volunteers: Not accepted

Summary

Successful embryo implantation is complicated process that requires synchrony between good-quality embryos and receptive endometrium. Human chorionic gonadotropin (hCG), is one of the initial embryonic signals and the major embryoendometrial relationship regulator. This study will be conducted to to investigate the role of parenteral hCG used for the transfer of cryopreserved- thawed embryos with HRT cycles in the outcome of artificially prepared frozen embryo transfer (FET) cycles.

Conditions

• hCG
• FET
• Frozen-thawed Embryo Transfe
• Human Chorionic Gonadotrophin

Interventions

Type	Name	Description
DRUG	Human Chorionic Gonadotrophin Intramuscular injection 10.000 IU	From the 12th to 13th day of the cycle when endometrium reached the optimal thickness ≥8 mm, group 1 (hCG) will receive 10.000 IU hCG intramuscular injection in the morning then vaginal suppository progesterone 400 mg twice a day will be started in the afternoon

Timeline

• Start date: 2020-01-01
• Primary completion: 2022-06-20
• Completion: 2022-07-30
• First posted: 2022-04-21
• Last updated: 2022-09-01

Locations

1 site across 1 country: Egypt