NCT05338411

Effect of Exogenous Growth Hormone on Ocular Findings

Effect of Exogenous Growth Hormone on Ocular Findings of Children With Precocious and Early Puberty: a Prospective Cohort Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 90 (estimated)
• Sponsor: Isfahan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 4 Years – 11 Years
• Healthy volunteers: Accepted

Summary

Body size and eye function play an essential role in adapting to the environment and human survival. Growth hormone is commonly recognized by its effect on the height of individuals; Although from an evolutionary perspective, the effects of growth hormone on eye development are more important. Although the effect of growth hormone on eye development has not been accurately determined, the results of a number of studies suggest the effect of growth hormone on eye development. Despite the large number of studies that have investigated the effects of growth hormone on height growth, there are few studies that have investigated the effects of growth hormone on the eye. To the best of our knowledge, no study has been conducted to investigate the effect of growth hormone on ocular findings of patients with early or precocious puberty. Therefore, we intend to investigate the effect of growth hormone on ocular findings of patients with early or precocious puberty.

Detailed description

Investigators will achieve the following data from the participants: 1. Demographics 2. Past medical history 3\. Bone and calendar age 4- Stage of puberty 5- Ocular examination 6\. Ocular biometry

Conditions

• Precocious Puberty
• Early Puberty
• Refraction Error

Timeline

• Start date: 2022-03-20
• Primary completion: 2023-10-22
• Completion: 2023-10-22
• First posted: 2022-04-21
• Last updated: 2022-04-21

Locations

2 sites across 1 country: Iran