Clinical Trials Directory

Trials / Completed

CompletedNCT05338021

Intrawound Administration of Vancomycin in TKA

Serum and Wound Vancomycin Levels Following Intrawound Administration in Primary Total Knee Arthroplasty

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
100 (actual)
Sponsor
The Affiliated Hospital of Qingdao University · Academic / Other
Sex
All
Age
50 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the intra-articular and serum levels of vancomycin over the first 24 hours postoperatively after intra-articular administration of a standard dose of vancomycin in primary total knee arthroplasty.

Conditions

Interventions

TypeNameDescription
PROCEDUREIntrawound administration of vancomycin after closure of the arthrotomyAfter closure of the arthrotomy, 1 g of vancomycin powder suspended in 30ml of normal saline was injected directly into the joint with an 18-gauge needle.

Timeline

Start date
2022-05-25
Primary completion
2022-09-07
Completion
2022-09-07
First posted
2022-04-20
Last updated
2023-01-19

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05338021. Inclusion in this directory is not an endorsement.