NCT05336981

Effect of Photobiomodulation for Patients With Xerostomia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Pia Lopez Jornet · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hyposalivation is a condition represented by a reduced salivary flow and may include symptoms such as mouth dryness (xerostomia), pain, loss of taste,dysphagia, and dysphonia, all of which greatly affect an individual's quality of life. The aim of the present study was analized the effects of low-level light therapy irradiation (photobiomodulation PBM) on salivary gland function in patients with hyposalivation

Detailed description

Inclusion criteria -the inclusion criteria for participating in the study were: age over 18 years; continuous xerostomia for over three months; and/or altered sialometry findings at baseline (salivary flow \< 0.1 mL/min). Exclusion criteria. : xerostomia as secondary to radiotherapy; patients with decompensated systemic disorders or cognitive problems The 60 individuals will be randomized in 2 groups: Group A (30 individuals submitted to treatment with a PBM) and Group B (30 individuals submitted to simulated PBM). A total of 60 patients with xerostomia were enrolled in the study and cited once a week for a period of 6 weeks treatment with diode laser (810nm, 6J/cm2) or sham treatment (according to the group).

Conditions

• Photobiomodulation
• Low-Level Light Therapy

Interventions

Type	Name	Description
RADIATION	Low-Level Light Therapy	The method consists of the application extraoral of low-intensity infrared laser in the major salivary glands-parotid, submandibular

Timeline

• Start date: 2020-01-01
• Primary completion: 2021-01-01
• Completion: 2022-01-26
• First posted: 2022-04-20
• Last updated: 2022-04-20

Locations

2 sites across 1 country: Spain