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Active Not RecruitingNCT05336266

A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma

IIT2021-16-Hendifar-KetoROCX: A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma

Status
Active Not Recruiting
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
28 (actual)
Sponsor
Andrew Hendifar, MD · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to see if taking ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is reasonable, safe and can stabilize or increase weight along with quality of life in pancreatic cancer patients.

Detailed description

The main things that will happen in this study are: patients will be administered ketorolac for 5 days, blood draws, completion of questionnaires, monitoring physical activity and sleep by wearing a study-provided FitBit along with weight using a study-provided smart scale.

Conditions

Interventions

TypeNameDescription
DRUGKetorolac TromethamineTrial treatment of ketorolac 10mg orally four times a day for 5 consecutive days

Timeline

Start date
2022-07-01
Primary completion
2025-02-19
Completion
2026-12-05
First posted
2022-04-20
Last updated
2026-01-06

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05336266. Inclusion in this directory is not an endorsement.

A Feasibility Study of Ketorolac Treatment for Cachexia in Patients With Advanced Pancreatic Ductal Adenocarcinoma (NCT05336266) · Clinical Trials Directory