NCT05325489

Comparison of Nebulized Budesonide and Intranasal Budesonide Spray in Children With Adenotonsillar Hypertrophy

Comparison Between the Effect of Nebulized Budesonide and Intranasal Budesonide Spray on Children With Adenotonsillar Hypertrophy: A Randomized Controlled Clinical Trial

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Second Xiangya Hospital of Central South University · Academic / Other
• Sex: All
• Age: 3 Years – 10 Years
• Healthy volunteers: Not accepted

Summary

Budesonide is one of the most common drugs uesd in children with adenotonsillar hypertrophy. This study aim to evaluate the efficacy of a short course of budesonide inhalation suspension via transnasal nebulization in children with adenotonsillar hypertrophy. The second aim is to compare budesonide inhalation suspension with budesonide aqueous nasal spray in adenotonsillar hypertrophy treatment.

Conditions

• Snoring
• Mouth Breathing

Interventions

Type	Name	Description
DRUG	Nebulized Budesonide	use 0.5mg/2ml Pulmicort Respules BIS QD and oral montelukast sodium chewable tablets 4mg QD
DRUG	Intranasal Budesonide Spray	nasal spray 100μg QD and oral montelukast sodium chewable tablets 4mg QD

Timeline

• Start date: 2022-04-01
• Primary completion: 2023-11-01
• Completion: 2024-09-01
• First posted: 2022-04-13
• Last updated: 2022-04-22

Locations

1 site across 1 country: China