NCT05318911

Antithrombotic Activities of a Novel Yogurt Drink

Antithrombotic Activities of a Novel Yogurt Drink: a Dietary Intervention Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Limerick · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study aims to evaluate antithrombotic activities of novel yoghurt drink in healthy adult volunteers

Detailed description

This randomized controlled, double-blinded crossover study aims to investigate the antithrombotic activities of a novel yoghurt drink in healthy adult volunteers. It is anticipated that the novel drink containing beneficial polar lipids will reduce platelet aggregation in participants and consequently decrease the onset of cardiovascular disease. In Phase I, the subjects will provide blood samples after overnight fasting and then take either a yoghurt drink (YD) or placebo (that does not contain polar lipids) daily for 4 weeks. Following this period, they will again provide blood samples. Then, after a 2-week washout period in which the subjects do not take any yoghurt or placebo drink , Phase II of the clinical trial will commence. This is the crossover phase in which subjects who took YD will now be given a placebo drink, and vice versa, over 4 weeks. A total of 80 blood samples will be collected for analysis.

Conditions

• Cardiovascular Diseases

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Novel yogurt drink	Novel ovine yogurt drink containing polar lipids
OTHER	Placebo Drink	Placebo drink (skimmed milk)

Timeline

• Start date: 2022-05-01
• Primary completion: 2022-09-30
• Completion: 2022-09-30
• First posted: 2022-04-08
• Last updated: 2022-11-07

Locations

1 site across 1 country: Ireland