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Trials / Terminated

TerminatedNCT05316116

Siltuximab in Large Granular Lymphocytic Leukemia (LGLL)

A Pilot Study of Siltuximab in Large Granular Lymphocytic Leukemia (LGLL)

Status
Terminated
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
6 (actual)
Sponsor
H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to evaluate the safety and effectiveness of siltuximab for participants being treated for large granular lymphocytic leukemia (LGLL).

Conditions

Interventions

TypeNameDescription
DRUGSiltuximabSiltuximab will be given on day 1 of each cycle. The dose will be 11 mg/kg given over 1 hour by intravenous infusion. Each cycle is three weeks (+-3 days).

Timeline

Start date
2023-02-15
Primary completion
2024-10-18
Completion
2024-10-18
First posted
2022-04-07
Last updated
2026-02-05

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05316116. Inclusion in this directory is not an endorsement.

Siltuximab in Large Granular Lymphocytic Leukemia (LGLL) (NCT05316116) · Clinical Trials Directory