NCT05313425

Effect of Ectoine After Photorefractive Keratectomy (PRK).

Effect of Ectoine on Stromal Haze, Wound Healing and Pain After Photorefractive Keratectomy.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 15 (estimated)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 19 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

This is a comparative, open label, parallel group, non interventional study aims to assess the effect of Ectoine containing eye drops on stromal haze, pain and epithelial healing after Photorefractive keratectomy (PRK). The patient apply Ectohylo eye drops (Ectoine +Sodium Hyauronate) in the right eye and Polyfresh Extra eye drops (Carboxymethyl cellulose + Sodium Hyauronate ) in the left eye plus the routine post PRK treatment in both eyes. Post operative pain , epithelial healing and corneal densitometry is observed in both eyes.

Detailed description

Photorefractive keratectomy (PRK) is a commonly used operation for laser vision correction. The main fears of this type of laser vision correction is corneal haze, delayed epithelial healing and postoperative severe pain. Ectoine is a natural compound that has the ability to protect biological membranes from damage and environmental effects. This study assess the use of Ectoine containing eye drops to protect the bare ocular surface and reduce inflammation after PRK that will inturn is expected to affect the post operative corneal haze, pain, and epithelial healing .

Conditions

• Photorefractive Keratectomy
• Corneal Haze

Interventions

Type	Name	Description
OTHER	Ectohylo (R) eye drops	using Ectohylo eye drops post operative after PRK in the right eyes of the patients

Timeline

• Start date: 2022-01-01
• Primary completion: 2022-05-01
• Completion: 2022-10-01
• First posted: 2022-04-06
• Last updated: 2022-04-06

Locations

1 site across 1 country: Egypt