NCT05313126

Immuno-epidemiological and Socio-behavioral Evaluation of Release of Sterile Male Aedes Albopictus Mosquitoes on Human-vector Contacts

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 500 (estimated)
• Sponsor: Institut de Recherche pour le Developpement · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This trial is based on 2 complementary components, named ExpAlbo Biomarker and CAPAlbo Questionnaire 1. ExpAlbo Biomarker (Exposure to the Aedes albopictus mosquito): This component concerns the epidemiological evaluation of the effectiveness of the release of sterile male mosquitoes on the level of exposure of individuals to the bites of the tiger mosquito through the use of a new immunological biomarker of the human-vector contact, developed over the past 20 years by the IRD-MIVEGEC team. Indeed, when a person is bitten by a mosquito, he or she develops a defence reaction, called an immune reaction, against the mosquito's saliva. The main objective of this study is to measure this immune response, and more specifically the antibody response specifically directed against compounds (peptide = small fragment of a protein) in mosquito saliva, and to determine whether this anti-saliva antibody response, and therefore exposure to mosquito bites, decreases when the mosquito control strategy is applied. 2. CAPAlbo Questionnaire: This component is concerned with assessing the impact of sterile male mosquito releases on perceptions and practices related to exposure to Aedes albopictus based on population-based questionnaire surveys. The main objective of these surveys is to determine whether changes in objective exposure to Aedes albopictus mosquitoes are associated with changes in the perception of the nuisance and in the lifestyle habits of respondents, particularly those related to the prevention of mosquito bites (such as the use of repellents or mosquito nets).

Conditions

• Mosquito Bite

Interventions

Type	Name	Description
OTHER	sterile insect technique (TIS)	Sterile male Aedes albopictus mosquitos are released in the area/neighborhood

Timeline

• Start date: 2021-11-09
• Primary completion: 2023-06-01
• Completion: 2023-06-01
• First posted: 2022-04-06
• Last updated: 2022-04-06

Locations

1 site across 1 country: France