NCT05312528

Evaluation of New Biomarkers in Stage 3 and 4 Endometriosis

Diagnostic Value of Annexin V, sVCAM-1, sICAM-1, Vascular Endothelial Growth Factor, TNF Alpha and Interleukin-6 in Ovarian and Deep Infiltrating Endometriosis, the Changes of These Markers in the Postoperative Period

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 79 (actual)
• Sponsor: Bagcilar Training and Research Hospital · Other Government
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The diagnostic value of Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and Proinflammatory cytokines (TNF-a and interleukin-6) in ovarian endometriosis and deep infiltrating endometriosis, their levels in organ-specific involvement, their relationship with symptoms, and the changes of these markers in the postoperative period will be evaluated.

Detailed description

Serum Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and proinflammatory cytokines (TNF-a and interleukin-6) values were studied by taking blood samples from all patients before and three months after the operation.

Conditions

• Endometriosis

Interventions

Type	Name	Description
PROCEDURE	endometriosis surgery	Laparoscopy was performed in the follicular phase of the woman's menstrual cycle and all recognizable endometriotic lesions were treated by bipolar coagulation, resection of endometriotic nodules and ovarian cystectomy.
PROCEDURE	other benign condition surgeries	ovarian cystectomy, bilateral tubal ligation, myomectomy etc.

Timeline

• Start date: 2018-02-01
• Primary completion: 2019-02-01
• Completion: 2019-03-01
• First posted: 2022-04-05
• Last updated: 2022-04-05

Locations

1 site across 1 country: Turkey (Türkiye)