NCT05310565

The Effects of Chiropractic in Adults With Colon Cancer

The Effects of Chiropractic Care on the Quality of Life and Autonomic Nervous System in Adults With Colon Cancer: a Single-arm Pilot Trial

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Life University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objectives of this single-arm pilot trial are to investigate the feasibility of our protocol in terms of 1) recruitment, 2) adherence, 3) tolerability, 4) acceptability and 5) retention. We aim to recruit 20 participants with advanced colon cancer (stage 3-4) who will have assessments of their autonomic nervous system function, carcinoembryonic antigen (CEA) levels, and patient-reported outcomes. Thereafter, patients will be directed to a nearby field clinic to receive twice-weekly cervical assessments \& high-velocity, low-amplitude (HVLA) cervical adjustments for a period of 6 weeks. Re-assessments will be performed following 2 weeks and 6 weeks of chiropractic care.

Detailed description

After providing informed consent, individuals will undergo 6 weeks of chiropractic care. Throughout these 6 weeks there will be three assessments (Day 1, Week 2, and Week 6) that each include the following: 1. Isometric hand grip 2. Postural challenge 3. Patient-reported outcome surveys 4. Off-site blood draw for CEA level testing (only Day 0 and Week 6) Each assessment will consist of the following recordings: 1. Electrodermal activity \[EDA\] 2. Impedance cardiography \[ICG\] 3. Electrocardiogram \[ECG\]

Conditions

• Colon Cancer Stage III
• Colon Cancer Stage IV

Interventions

Type	Name	Description
PROCEDURE	HVLA cervical chiropractic adjustments	Chiropractic high velocity low amplitude adjustment

Timeline

• Start date: 2025-01-01
• Primary completion: 2025-03-01
• Completion: 2025-03-01
• First posted: 2022-04-05
• Last updated: 2024-04-03

Locations

1 site across 1 country: United States