NCT05310318

Prognosis of Low-grade Endometrial Stromal Sarcoma

Surgical and Reproductive Results of Fertility-sparing Treatment for Low-grade Endometrial Stromal Sarcoma: A Retrospective Cohort Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: Lei Li · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

This study is to investigate the survival outcomes and fertility outcomes in patients with uterine low-grade endometrial stromal sarcoma (LGESS) treated in Peking Union Medical College Hospital. All primary and recurrent LGESS patients will be enrolled. The study will collect retrospectively data consisting of epidemiological characteristics, surgical, medical treatment and adjuvant therapy. Details about recurrence, mortality, pregnancy and obstetrical outcomes are also followed as primary endpoints. Fertility-sparing procedures, including uterine-sparing and ovary-sparing surgeries will be recorded specifically.

Conditions

• Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis)
• Fertility-sparing Surgery
• Survival Outcomes
• Fertility Outcomes
• Recurrence
• Hormone Therapy
• Adjuvant Therapy

Interventions

Type	Name	Description
PROCEDURE	Surgical treatment with and without fertility-sparing procedures	Patients accepted surgeries for LGESS and relevant adjuvant therapy if indicated.

Timeline

• Start date: 2022-03-26
• Primary completion: 2024-03-26
• Completion: 2025-03-26
• First posted: 2022-04-04
• Last updated: 2022-04-04

Locations

1 site across 1 country: China