NCT05309720

Dermal Substitution in Pediatric Burns

Dermal Substitution in Paediatric Burns: A Prospective Case Series

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: Radboud University Medical Center · Academic / Other
• Sex: All
• Age: 15 Years
• Healthy volunteers: Not accepted

Summary

The standard treatment of deep dermal to full thickness burns is surgical removal of the burn followed by skin transplantation. Dermal substitutes are increasingly used in the treatment of deep burns to replace lost dermis. Preservation of the collagen and elastin in the acellular human dermal substitute Glyaderm provides a more elastic scar. It is unknown what the effect of Glyaderm on scar quality is in a solely paediatric population. The objective of this case series is to investigate scar maturation and scar quality when applying Glyaderm in deep dermal to full thickness burns in a pediatric population aged ≤15 years old.

Conditions

• Burns
• Burn Scar

Interventions

Type	Name	Description
PROCEDURE	Glyaderm	All included patients will undergo full thickness removal of the burned skin or adequate debridement of all necrotic tissue. Next, the dermal substitute Glyaderm followed by a split thickness skin graft will be transplanted on the wound.

Timeline

• Start date: 2022-09-01
• Primary completion: 2025-11-01
• Completion: 2025-11-01
• First posted: 2022-04-04
• Last updated: 2024-04-12

Locations

1 site across 1 country: Netherlands