NCT05309538

Paroxysmal Positional Vertigo & Repositioning Maneuvers

Effect of Modified Epley's & Semont's Maneuvers With or Without Beta-histine on Benign Paroxysmal Positional Vertigo: A Randomized Control Trail

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (actual)
• Sponsor: Neuro Counsel Hospital, Pakistan · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

: Benign Paroxysmal Positional Vertigo is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability. Various treatment options are available including pharmacotherapy and vestibular rehabilitation with varied results

Detailed description

Objective: The objective of this study was to compare the efficacy of Modified Epley \& Semont's maneuver with and without Betahistine for BPPV Material \& Methods: The study was a single blind randomized control trail. Total number of patients were 97 as calculated by Epitool calculator. Duration of the study was of one year from 2 January 2021 to 1st January 2022. Out of a total 97 patients, 90 met the inclusion criteria. These participants were randomized by lottery method into two equal groups. Group A (control group) was receiving both maneuvers only while group B (experimental group) included participants receiving betahistine along with both maneuvers. The impact of dizziness and quality of life was measured through EQ-5D-5L questionnaire and dizziness handicap inventory (DHI) in order to analyze the effectiveness of treatments. Pre and Post treatment results were compared within group by Wilcoxon rank test and for between groups, Mann Whitney U test was performed

Conditions

• Benign Paroxysmal Positional Vertigo

Interventions

Type	Name	Description
OTHER	Modified eply & Semont maneuver	repositioning maneauvers
OTHER	betahistine & Modified eply & Semont maneuver	antihistamine plus repositioning maneuvers

Timeline

• Start date: 2021-01-02
• Primary completion: 2022-01-01
• Completion: 2022-01-01
• First posted: 2022-04-04
• Last updated: 2022-04-04

Locations

1 site across 1 country: Pakistan