Trials / Unknown
UnknownNCT05304741
The Culture of Advanced/Recurrent/Metastatic Colorectal Cancer Organoids and Drug Screening
Drug Screening of Patient-derived Organoids From Advanced/Recurrent/Metastatic Colorectal Cancer Culture to Personalized Therapy, an Exploratory Research
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- Chongqing University Cancer Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- —
Summary
The study aims to establish an organoids platform and apply them to screen drugs for advanced/recurrent/metastatic colorectal cancer patients.
Detailed description
The study was designed as a prospective, observational clinical trial in a single center. We establish organoids derived from patients with advanced/recurrent/metastatic colorectal cancer. Organoids will be validated with a combination of Next Generation Sequencing (NGS) analysis and histopathology. Drug screening assay will be performed on organoids with the chemotherapy and targeted agents, and the sensitivity and speciality will be compared with the clinical practice.
Conditions
Timeline
- Start date
- 2020-01-01
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
- First posted
- 2022-03-31
- Last updated
- 2023-08-31
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT05304741. Inclusion in this directory is not an endorsement.