NCT05302687

Probiotic Modulates Vaginal Microflora

Use of Probiotic to Modulate Vaginal Microflora and General Women's Health

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 112 (actual)
• Sponsor: Min-Tze LIONG · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the effects of oral administration of probiotic at 9 log colony forming unit (CFU)/day on vaginal microbiota profiles compared to placebo via the use of vaginal self-swab microbiota profiling.

Detailed description

1. To evaluate differences in general women's health of women on probiotic and placebo via the use of questionnaire. 2. To evaluate differences in immunity of women on probiotic and placebo via blood immunity profiling. 3. To evaluate differences in gut microbiota profiles of women on probiotic and placebo via blood fecal microbiota profiling.

Conditions

• Microbial Colonization

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Probiotic	This project aims to evaluate differences in general women's health of women on probiotic and placebo via the use of questionnaire and evaluate differences in immunity of women on probiotic and placebo via blood immunity profiling. To evaluate differences in gut microbiota profiles of women on probiotic and placebo via blood fecal microbiota profiling.
DIETARY_SUPPLEMENT	placebo	This project aims to evaluate differences in general women's health of women on probiotic and placebo via the use of questionnaire and evaluate differences in immunity of women on probiotic and placebo via blood immunity profiling. To evaluate differences in gut microbiota profiles of women on probiotic and placebo via blood fecal microbiota profiling.

Timeline

• Start date: 2022-01-15
• Primary completion: 2024-03-18
• Completion: 2024-03-18
• First posted: 2022-03-31
• Last updated: 2024-06-21

Locations

1 site across 1 country: Malaysia