NCT05302219

Plethysmography Curve Variability Depending on the Breath Cycle

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Czech Technical University in Prague · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The aim of the study is to analyze the variability of plethysmography curve depending on the breath cycle (respiratory rate and tidal volume).

Detailed description

The plethysmography curve measured by finger sensors using pulse oximetry shows the changes in blood volume at the measured site. The presence of respiratory information within the pulse oximeter signal is a well-documented phenomenon. However, previous studies have mainly focused on extracting the respiratory rate from the plethysmography curve. The aim of this study is to analyze the variability of plethysmography curve as a function of both respiratory rate and tidal volume. Furthermore, the aim is to analyze the possibilities of apneic pause detection from the plethysmography curve.

Conditions

• Apnea
• Circulatory; Change
• Respiration

Interventions

Type	Name	Description
OTHER	Respiratory rate	The participant alternates respiratory rates of 30, 15 and 7.5 breaths/min. Breathe each frequency for 2 minutes with a one-minute break.
OTHER	Tidal volume	The participant alternates tidal volumes of approx. 2, 1 and 0.5 litres. Breathe each tidal volume for 2 minutes with a one-minute break.
OTHER	Apnea	The participant simulates three apneic pauses lasting 1 minute with a two-minute break.

Timeline

• Start date: 2022-03-10
• Primary completion: 2022-06-30
• Completion: 2022-06-30
• First posted: 2022-03-31
• Last updated: 2025-03-25

Locations

1 site across 1 country: Czechia