NCT05301634

Comparison Between Bilateral Infraorbital Block Versus Intranasal Bupivacaine in Transsphenoidal Pituitary Adenoma Resection

Comparison Between Hemodynamic Effect of Bilateral Infraorbital Block Versus Intranasal Application of Bupivacaine in Patients Undergoing Transsphenoidal Pituitary Adenoma Resection.A Comparative Randomized Controlled Study

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

The study will evaluate the efficacy of bilateral infraorbital nerve block versus preoperative nasal packing with long-acting local anesthetic bupivacaine in term of maintaining hemodynamics intraoperative within 20% below baseline to achieve adequate hypotensive anesthesia and longer duration of postoperative analgesia up to 24 hours in patients undergoing transsphenoidal pituitary adenoma resection.

Conditions

• Intraoperative Hypertension

Interventions

Type	Name	Description
PROCEDURE	infraorbital block	the patients will receive bilateral infraorbital block
PROCEDURE	topical intranasal bupivacaine	the patients will receive topical intranasal application of bupivacaine

Timeline

• Start date: 2022-04-02
• Primary completion: 2025-07-30
• Completion: 2025-12-15
• First posted: 2022-03-31
• Last updated: 2025-12-30

Locations

1 site across 1 country: Egypt