NCT05301348

In Vivo Detection of Circulating Clots in Patients With Thromboembolism

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Subjects with thromboembolic disease or at high-risk for thromboembolic conditions diagnosed with ultrasound or other standard of care techniques will be recruited to estimate the feasibility of a device to detect in vivo CBCs.

Detailed description

There are no current gold standards to detect circulating blood clots. The sensitivity of most current methods to detect CBCs is poor when low numbers are present in the host. A novel method of detecting circulating blood clots, PAFC, may improve detection of CBCs and, if so, ultimately may reduce complications related to previously undetected clots.

Conditions

• Thromboembolism

Interventions

Type	Name	Description
DEVICE	Photoacoustic Flow Cytometry	Detection of circulating blood clots

Timeline

• Start date: 2023-07-26
• Primary completion: 2026-12-31
• Completion: 2027-01-31
• First posted: 2022-03-29
• Last updated: 2026-02-19

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study