Trials / Recruiting
RecruitingNCT05301283
Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma
Phase 2 Clinical Trial of Radiomic Habitat-Directed Radiation Dose Escalation for High-Grade Soft Tissue Sarcoma
- Status
- Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 43 (estimated)
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the study is to utilize radiomic images to precisely locate areas of tumor that can be treated with dose escalation radiation therapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Intensity Modulated Radiation Therapy (IMRT) | Participants will be treated with intensity modulated radiation therapy (IMRT) with photons, which is FDA (U.S. Food and Drug Administration) approved radiation delivery system. |
| DIAGNOSTIC_TEST | MRI | Participants will receive pretreatment diagnostic MRIs to generate MRI habitats. These images will identify radioresistant cells within tumor. |
Timeline
- Start date
- 2022-05-18
- Primary completion
- 2026-08-01
- Completion
- 2026-08-01
- First posted
- 2022-03-29
- Last updated
- 2025-12-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT05301283. Inclusion in this directory is not an endorsement.