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Trials / Completed

CompletedNCT05297565

A Study to Compare Nivolumab Administered Subcutaneously vs Intravenous in Melanoma Participants Following Complete Resection

A Phase 3, Open Label, Randomized, Non-Inferiority Pharmacokinetic Study of Nivolumab Subcutaneous (Nivo SC) Versus Intravenous (Nivo IV) Administration in Participants With Stage IIIA/B/C/D or Stage IV Adjuvant Melanoma Following Complete Resection

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
14 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the safety and tolerability of subcutaneous nivolumab vs intravenous nivolumab in participants with completely resected Stage IIIA/B/C/D or Stage IV melanoma.

Conditions

Interventions

TypeNameDescription
BIOLOGICALNivolumab/rHuPH20Specified dose on specified days
BIOLOGICALNivolumabSpecified dose on specified days

Timeline

Start date
2022-08-02
Primary completion
2024-02-08
Completion
2024-02-08
First posted
2022-03-28
Last updated
2025-02-27
Results posted
2025-02-27

Locations

16 sites across 7 countries: United States, Australia, Belgium, Italy, Poland, Spain, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT05297565. Inclusion in this directory is not an endorsement.

A Study to Compare Nivolumab Administered Subcutaneously vs Intravenous in Melanoma Participants Following Complete Rese (NCT05297565) · Clinical Trials Directory