NCT05295329

Effect of Compound Danshen Dripping Pills on Diabetic Patients With Coronary Microcirculation Disturbance

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Ruijin Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Most patients with diabetes complicated with microvascular circulation disorder have normal coronary angiography but still suffer from chest tightness, chest pain and so on. Early dysfunction of coronary microcirculation is an important reason for it. It is also an important factor leading to poor prognosis of patients with diabetes. For these patients, there are still no drugs to improve microcirculation disorders. Compound Danshen dropping pills have the effects of anti-oxidation, anti-inflammatory, protecting endothelium, inhibiting the formation of atherosclerotic plaque and intimal hyperplasia, reducing oxygen consumption, improving energy metabolism, protecting cardiomyocytes, inhibiting platelet adhesion and aggregation, and improving microcirculation. However, there is a lack of clinical evidence that compound Danshen dripping pills can improve the cardiac microcirculation disturbance in diabetic patients with microangio angina. Therefore, the aim of this study was to observe the effect of Compound Danshen Dripping Pills on coronary microcirculation disturbance in diabetic patients.

Conditions

• Diabetes

Interventions

Type	Name	Description
DRUG	Compound Danshen Dropping Pills	use Compound Danshen Dropping Pills
DRUG	Placebo	use placebo

Timeline

• Start date: 2022-04-01
• Primary completion: 2022-09-30
• Completion: 2022-12-30
• First posted: 2022-03-25
• Last updated: 2022-03-25

Locations

7 sites across 1 country: China