NCT05295095

Does Positive Pressure Extubation Reduce Postoperative Desaturation?

The Value of Positive Pressure Extubation in Reducing Postoperative Desaturation Episodes in Adults Undergoing Abdominal Surgery

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 264 (estimated)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Single-center, prospective, controlled, parallel, randomized, single-blind study comparing the conventional extubation technique to two positive pressure extubation techniques on postoperative desaturations

Detailed description

Study realise on university hospital on Lille in France. Patients inclusion is prospective and randomised in three groups. First group : extubation is realised with aspiration in tracheal tube during removal tube Second group : extubation is realised without aspiration but with APL valve set to 20cmH20 Third group : extubation is realised without aspiration but with ventilator parameters were set for PSV mode (inspiratory pressure of 10cmH2O and PEEP identical to that administered in the operating room

Conditions

• Extubation
• Postoperative Complications
• Lung Ultrasound Score

Interventions

Type	Name	Description
PROCEDURE	positive pressure during extubation procedure	positive pressure during extubation procedure

Timeline

• Start date: 2022-06-29
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2022-03-24
• Last updated: 2025-12-26

Locations

1 site across 1 country: France