Clinical Trials Directory

Trials / Completed

CompletedNCT05292040

A Study of LY3857210 in Healthy Participants

An Adaptive Design, Phase 1, Open-label Study to Investigate Receptor Occupancy in Brain After Single Oral Doses of LY3857210 as Measured by Positron Emission Tomography (PET) With the Radioligand [18F]-LY3818850 in Healthy Participants

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
10 (actual)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The main purpose of this study is to evaluate the presence of study drug LY3857210 in the brain measured by positron emission tomography (PET) with the radioligand \[18F\]-LY3818850 in healthy participants. The safety and tolerability of LY3857210 will also be evaluated. The study will last up to approximately 6 weeks for each participant and may include up to four visits to the study center.

Conditions

Interventions

TypeNameDescription
DRUGLY3857210Administered orally.

Timeline

Start date
2022-03-17
Primary completion
2022-12-14
Completion
2022-12-14
First posted
2022-03-23
Last updated
2023-03-01

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05292040. Inclusion in this directory is not an endorsement.