NCT05291663

Effect of Accelerated RTH in Squamous Cell Carcinoma in Head and Neck

Retrospective Study of Effect of Accelerated Radiation Therapy , Six Fractions Per Week , for Squamous Cell Carcinoma of Head and Neck.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

Evaluation of the efficacy of the accelerated radiotherapy in squamous cell carcinoma of head and neck

Detailed description

* HNSCC is the sixth most common cancer worldwide, with 890.000 new cases and 450.000 deaths in 2018. * The incidence of HNSCC continues to rise and is anticipated to increase by 30% (that is, 1.08 million new cases annually) by 2030. * Squamous cell carcinoma constitutes 90% of all head and neck cancers and it predominates in males. * Risk factors such as cigarette consumption and alcohol consumption, are well established. * Treatment decisions are guided by clinic-pathologic factors such as age and stage. * Treatment of the majority of patients with HNSCC requires multimodality approaches. * Radiotherapy or surgery alone can be considered as the standard treatment modality for patients having early head and neck squamous cell carcinoma. * When conventionally fractionated radiotherapy is used, long-term tumor control can be achieved in less than 30% of patients with advanced head and neck carcinomas.

Conditions

• Head and Neck Squamous Cell Carcinoma

Timeline

• Start date: 2022-03-20
• Primary completion: 2023-03-20
• Completion: 2023-12-20
• First posted: 2022-03-23
• Last updated: 2022-03-23