NCT05287633

Proton Pump Inhibitors Effects on Dyspepsia During Ramadan Fasting

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 500 (actual)
• Sponsor: University of Monastir · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. The investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the signs of dyspepsia during Ramadan compared to placebo.

Detailed description

evaluate the interest of proton pump inhibitors in subjects with or with GI symptoms who intend to observe fasting in Ramadan. Investigators will compare the effectiveness of proton pump inhibitors to prevent or reduce the signs of dyspepsia during at least Ramadan compared to placebo. The study will be conducted at least from April 2019 to at least June 2030.The study is prospective, two parallel groups, randomized controlled and double blind.

Conditions

• Dyspepsia

Interventions

Type	Name	Description
DRUG	Esomeprazole	Patients are given a box of capsules of which they take 1capsule/day during the month of ramadan
DRUG	Placebo	Patients are given a box of capsules of which they take 1capsule/day during the month of ramadan

Timeline

• Start date: 2020-01-20
• Primary completion: 2020-12-15
• Completion: 2024-12-30
• First posted: 2022-03-18
• Last updated: 2025-02-25

Locations

1 site across 1 country: Tunisia