NCT05281952

Medico-economic Evaluation of Management Strategies for Severe Epistaxis

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 180 (estimated)
• Sponsor: University Hospital, Toulouse · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Current recommendations consider surgical ligation and supra-selective embolization as equivalent in terms of efficacy and there is no clear consensus to choose between one and the other technique. In the absence of medico-economic studies, these recommendations could not be based on any differences in efficiency between the two techniques. The management of patients with severe non-traumatic epistaxis remains controversial and varies according to the hospital and/or university centers. In practice, the use of one or the other technique depends on the habits of each reference center.

Detailed description

The hypothesis is that early ligation of the sphenopalatine arteries would reduce the costs of care for the community while improving the quality of life of patients compared to supra-elective embolization. This medico-economic superiority could go through: * reduction in the number of recurrences * reduction in the length of hospital stays. * reduction in the cost of postoperative care. * reduction of iatrogenic complications * improvement of functional suites upon return home. * Tertiary prevention of dependency, particularly among the elderly

Conditions

• Epistaxis

Interventions

Type	Name	Description
PROCEDURE	endoscopic ligation	the surgical ligation of one or both sphenopalatine arteries by endoscopic way.
PROCEDURE	Supra-selective embolization	occlusion of the terminal branches of the nasal external carotid artery.

Timeline

• Start date: 2023-05-01
• Primary completion: 2026-12-01
• Completion: 2026-12-01
• First posted: 2022-03-16
• Last updated: 2023-08-29

Locations

1 site across 1 country: France