NCT05278260

Hydrogen-rich Water and Treatment of Mucositis Caused by Radiation Therapy in Head and Neck Cancer Patients

Hydrogen Rich Water to Mitigate Acute Mucositis During Radiation Therapy

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Stony Brook University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study explores the effects of hydrogen-rich water on alleviating the radiation-induced acute mucositis in head and neck cancer patients

Conditions

• Mucositis Oral

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Hydrogen tablets	Participants will drink up to 1000 ml (34 fl. oz.) of water daily supplemented with a tablet that releases molecular hydrogen, for the duration of the radiation therapy
DIETARY_SUPPLEMENT	Control	Participants will drink up to 1000 ml (34 fl. oz.) of water daily supplemented with a tablet that does not release any molecular hydrogen, for the duration of the radiation therapy

Timeline

• Start date: 2022-05-25
• Primary completion: 2024-11-13
• Completion: 2024-11-13
• First posted: 2022-03-14
• Last updated: 2025-05-14

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study