NCT05276167

Hyperthermic Intravesical Perfusion for Muscle-invasive Bladder Urothelial Carcinoma

The Effect of Hyperthermic Intravesical Perfusion on the Risk of Intraoperative Implantation of Muscle-invasive Bladder Urothelial Carcinoma and Its Safety Analysis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Henan Cancer Hospital · Other Government
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the effect of hyperthermic intravesical perfusion on the risk of intraoperative implantation of muscle-invasive bladder urothelial carcinoma and its safety.

Detailed description

The participants will be divided into two groups (the experimental group and control group). Participants in the experimental group will be treated with hyperthermic intravesical perfusion before receiving radical cystectomy. Participants in the control group will receive radical cystectomy alone. After follow-up, the effect of hyperthermic intravesical perfusion on the risk of intraoperative implantation of muscle-invasive bladder urothelial carcinoma and its safety will be evaluated.

Conditions

• High-Risk, Non-Muscle Invasive Bladder Urothelial Carcinoma
• Perfusion; Complications
• Intraoperative Complications

Interventions

Type	Name	Description
DEVICE	hyperthermic intravesical perfusion	Participants in the experimental group will be treated with hyperthermic intravesical perfusion before receiving radical cystectomy

Timeline

• Start date: 2022-06-06
• Primary completion: 2024-12-01
• Completion: 2025-12-01
• First posted: 2022-03-11
• Last updated: 2022-09-16

Locations

1 site across 1 country: China