NCT05274906

Red and Processed Meat Effects on the Metabolome and Microbiome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 23 (actual)
• Sponsor: Fred Hutchinson Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This controlled feeding trial will identify biomarkers in the metabolome and microbiome that may differ when consuming a healthy diet with or without red and processed meat.

Detailed description

This is a randomized cross-over feeding trial to test whether red and processed meat consumption, in the context of a controlled diet based on HEI-2015, will cause shifts in the metabolome and the microbiome compared to a controlled HEI-2015 diet with no red or processed meat. Twenty healthy adult volunteers will consume two diets in random order: 1) Diet A is based on the Healthy Eating Index-2015 (HEI-2015) and includes no red or processed meat; 2) Diet B is based on the Healthy Eating Index-2015 and includes red and processed meat (HEI-2015-M) as some of the protein sources. Both diet periods last 21 days and an approximately 21-day washout period occurs between diets.

Conditions

• Controlled Feeding Trial
• Healthy Eating Index
• Red Meat
• Meat

Interventions

Type	Name	Description
OTHER	Randomized, cross-over controlled feeding trial testing a Healthy Eating Index 2015 (HEI-2015) diet with and without red and processed meat	Healthy Eating Index-2015 (HEI-2015) with or without red/processed meat (HEI-2015-M)

Timeline

• Start date: 2021-11-16
• Primary completion: 2023-02-07
• Completion: 2023-02-07
• First posted: 2022-03-11
• Last updated: 2024-09-05
• Results posted: 2024-09-05

Locations

1 site across 1 country: United States