NCT05273710

Effects of Dietary Folate and Phytate Zinc Absorption: Zinc Amino Acid Complexes vs. Zinc-chloride

Comparison of the Effects of Dietary Folate and Phytate on the Absorption of Zinc From Either Zinc-amino Acids (ZnAA) or Zinc-chloride (ZnCl2)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: University of California, Berkeley · Academic / Other
• Sex: Male
• Age: 19 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine the effects of consuming a small breakfast of juice and toast with added phytate or with taking a folic acid supplement on the absorption of a small amount of zinc that is either bound to amino acids or to chloride or picolinate. The results of this study will provide new information on how components of diet (e.g., phytate, and folic acid) affect the absorption of different forms of dietary zinc (e.g., zinc bound to amino acids, zinc chloride, and zinc picolinate).

Conditions

• Dietary Zinc Absorption

Interventions

Type	Name	Description
OTHER	Regular toast and juice	Participants consume a single test meal composed of regular whole wheat toast and apple juice, and zinc absorption is measured.
OTHER	High phytate toast and juice	Participants consume a single test meal composed of high phytate whole wheat toast and apple juice, and zinc absorption is measured.
OTHER	Regular toast and juice, with folic acid	Participants consume a single test meal composed of regular whole wheat toast and apple juice, with 400 mcg folic acid; and zinc absorption is measured.

Timeline

• Start date: 2022-03-28
• Primary completion: 2022-11-16
• Completion: 2022-11-16
• First posted: 2022-03-10
• Last updated: 2022-12-21

Locations

1 site across 1 country: United States