NCT05272475

The Acute Effects of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Stony Brook University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Chamomile may possess anticoagulant effects based on the presence of coumarin-like compounds within the flower. This randomized complete crossover study will investigate the impact of chamomile ingestion acutely on coagulation.

Detailed description

Subjects will be enrolled into two groups in a crossover fashion upon obtaining written informed consent. The two intervention groups include (1) chamomile tea intake and (2) chamomile extract intake. Subjects will consume a single preparation of chamomile tea or extract capsule, and partake in a minimum of three days washout period between interventions. Screening assays of coagulation will be obtained immediately before the ingestion of chamomile, two hours after ingestion, and four hours after ingestion over the course of a single day.

Conditions

• Coagulation Disorder

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Chamomile Tea	Chamomile tea bags consumed by subjects as described in study arms section.
DIETARY_SUPPLEMENT	Chamomile Extract Capsule	Chamomile extract capsules consumed by subjects as described in "Experimental: Chamomile Extract Capsule" study arms section.

Timeline

• Start date: 2022-03-16
• Primary completion: 2022-05-12
• Completion: 2022-05-12
• First posted: 2022-03-09
• Last updated: 2022-06-10

Locations

1 site across 1 country: United States