NCT05269823

Topical Ice-therapy for Intravitreal Injections

Topical Ice-therapy for Pain Modulation During Intravitreal Injections: A Prospective Randomized Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: University of Minnesota · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Purpose: To examine the difference in patient's pain experience in the setting of intravitreal anti-VEGF injections with pretreatment of topical ice-therapy compared with no-ice.

Conditions

• Anesthesia; Hypothermia
• Injection Site Irritation

Interventions

Type	Name	Description
OTHER	Ice-therapy	Ice therapy will be provided prior to intravitreal injection provision
OTHER	No Ice-therapy	No additional intervention (i.e.) ice therapy will be provided prior to intravitreal injection provision

Timeline

• Start date: 2022-04-01
• Primary completion: 2025-04-30
• Completion: 2025-04-30
• First posted: 2022-03-08
• Last updated: 2025-08-22

Locations

1 site across 1 country: United States