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Active Not RecruitingNCT05267587

Preop fSRS for Resectable Brain Metastases

Pre-operative Hypofractionated Stereotactic Radiosurgery for Resectable Brain Metastases

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
49 (actual)
Sponsor
H. Lee Moffitt Cancer Center and Research Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine whether treatment with pre-operative hypofractionated stereotactic radiosurgery followed by surgery will improve time to local failure (TTLF) compared to the current standard of care.

Conditions

Interventions

TypeNameDescription
RADIATIONHypofractionated Stereotactic RadiosurgeryParticipants will be given hypofractionated stereotactic radiosurgery (fSRS) in 9 Gray Units (Gy) per fraction x 3 consecutive daily fractions (27 Gy total) to the index metastasis that will be resected.

Timeline

Start date
2022-03-11
Primary completion
2025-05-29
Completion
2026-08-21
First posted
2022-03-04
Last updated
2026-03-31

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05267587. Inclusion in this directory is not an endorsement.