NCT05266703

Defining the Serum Ferritin Concentration in Kenyan Women at Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,000 (actual)
• Sponsor: Swiss Federal Institute of Technology · Academic / Other
• Sex: Female
• Age: 18 Years – 28 Years
• Healthy volunteers: Accepted

Summary

The serum or plasma ferritin concentration (referred to hereafter as ferritin) is the most widely used indicator to detect iron deficiency and a low ferritin indicates depleted iron stores. However, the threshold ferritin that defines iron deficiency remains unclear and diagnostic ferritin cutoffs from expert groups vary widely. Our study aim is to define the ferritin in Kenyan young women at which the body senses iron depletion and begins to upregulate iron absorption from the diet; this approach could provide a functionally defined threshold of iron deficiency in Sub-Saharan African women.

Conditions

• Iron-deficiency
• Ferritin Threshold
• Iron Absorption
• Stable Iron Isotopes

Interventions

Type	Name	Description
OTHER	Isotopically labelled iron sulfate 15mg	test drink: water containing isotopic iron solution with vitamin C

Timeline

• Start date: 2022-02-18
• Primary completion: 2023-06-30
• Completion: 2023-06-30
• First posted: 2022-03-04
• Last updated: 2024-01-25

Locations

1 site across 1 country: Kenya