NCT05265507

Comparison of Postoperative Anti-nausea and Vomiting Effect Between Glycopyrronium and Ondansetron

Comparison of Anti-nausea and Vomiting Effect After Elective Surgery Undergoing General Anesthesia Between Glycopyrronium and Ondansetron: a Multi-center Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 480 (estimated)
• Sponsor: The Second Affiliated Hospital of Chongqing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

To compare the anti-nausea and vomiting effect between glycopyrronium and ondansetron for patients receiving elective surgery under general anesthesia. Based on this study the investigators intend to explore the feasibility of using glycopyrronium to prevent postoperative nausea and vomiting.

Conditions

• Postoperative Nausea and Vomiting

Interventions

Type	Name	Description
DRUG	Glycopyrronium	Glycopyrronium (0.2mg) was intravenously given at the ending of the surgery.
DRUG	Ondansetron	Glycopyrronium (4mg) was intravenously given at the ending of the surgery.

Timeline

• Start date: 2022-03-21
• Primary completion: 2023-05-30
• Completion: 2023-05-30
• First posted: 2022-03-03
• Last updated: 2023-02-24

Locations

1 site across 1 country: China