NCT05264532

Usefulness of Video-Based Intervention in Helping Participants Encourage Their Families to Get Tested for BRCA Gene Mutations

BRCAShare: Video Intervention for Relatives of BRCA Mutation-Positive Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 58 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This trial studies how well a video-based intervention works in helping participants encourage their families to get tested for BRCA gene mutations. Testing in families with BRCA gene mutations can allow for risk management and reduction with the overall goal of reducing cancer burden. Video-based intervention sent via text messages may help participants easily share information about BRCA gene mutations with family members.

Detailed description

PRIMARY OBJECTIVES: I. To understand whether the use of a video-based message to encourage cascade testing, delivered via short message service (SMS) (text message) or shared on social media, is superior to a written message as a method of information-sharing among families that have BRCA gene mutations. OUTLINE: Participants are randomized to 1 of 2 arms. ARM A: Participants receive a 2-minute information-graphic video via text message consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives that they can share with family via text message, email, or social media. ARM B: Participants receive family letter via U.S. postal service mail consisting of misconceptions and issues that may be paramount when discussing mutation status with relatives.

Conditions

• BRCA1 Gene Mutation
• BRCA2 Gene Mutation

Interventions

Type	Name	Description
OTHER	Informational Intervention	Receive information-graphic video
OTHER	Informational Intervention	Receive family letter
OTHER	Survey Administration	Ancillary studies

Timeline

• Start date: 2018-04-05
• Primary completion: 2025-06-07
• Completion: 2025-06-07
• First posted: 2022-03-03
• Last updated: 2026-02-10

Locations

1 site across 1 country: United States