Clinical Trials Directory

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UnknownNCT05263817

A Clinical Study of CD19/BCMA CAR-T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis

A Clinical Study on the Safety and Effectiveness of CD19/BCMA Chimeric Antigen Receptor T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis

Status
Unknown
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
75 (estimated)
Sponsor
Zhejiang University · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

A Clinical Study on the Safety and Effectiveness of CD19/BCMA Chimeric Antigen Receptor T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis

Detailed description

POEMS syndrome, amyloidosis, autoimmune hemolytic anemia, vasculitis and other diseases may only show local pathological damage or systemic lesions. If they are not diagnosed and treated in time or poorly controlled, they will progress as the course of the disease progresses. Risk of disability or even death.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCD19/BCMA CAR T-cellsEach subject receive CD19/BCMA CAR T-cells by intravenous infusion

Timeline

Start date
2021-10-08
Primary completion
2024-10-01
Completion
2024-10-01
First posted
2022-03-03
Last updated
2022-03-03

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05263817. Inclusion in this directory is not an endorsement.