NCT05263687

Exercise Testing in Diseases and Health

Cardio Pulmonary Exercise Testing (CPET) in Diseases and Health

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,000 (estimated)
• Sponsor: The Baruch Padeh Medical Center, Poriya · Other Government
• Sex: All
• Age: 4 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. CPET provides a full assessment of the physiologic responses of the pulmonary, cardiovascular, muscular, and cellular oxidative systems to exercise. The test progression include a incremental stepwise (on treadmill) or ramp control protocol (on bike ergometer ) to exhaustion. Measurement of respiratory gas exchange i.e. oxygen uptake, carbon dioxide, minute ventilation, other variables while monitoring ECG, blood pressure, pulse oximetry and exertion perceived (Borg Scale) during an incremental test . Aim: To compere exercise responses for maximal exercise testing with different population.

Detailed description

Each participants will conducted an exercise test on treadmill using Modified Bruce Protocol) or cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be use to collect and analysis gas exchange. 10 minute after the graded exercise test Supra maximal exercise test (SMT) will be done for 2 minutes one stage (treadmill protocol) or 10% at cycle protocol higher than highest load achieved in the incremental test. all outcome measurement will be collected. Exercise tolerance and responses will be assess using the data of : pulmonary gas exchange; cardiovascular performance, and skeletal muscle metabolism.

Conditions

• Exercise Test

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Maximal exercise test	Each participants will conduct a spirometry test and exercise test on treadmill (using Modified Bruce Protocol) or cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be used to collect and analysis gas exchange, ECG, gas volume in addition rating of perceived exertion will be asked.

Timeline

• Start date: 2017-08-30
• Primary completion: 2025-03-19
• Completion: 2025-12-30
• First posted: 2022-03-02
• Last updated: 2022-03-21

Locations

1 site across 1 country: Israel