NCT05263362

An Integrated Optimization of Surgery and Radiotherapy Techniques to Improve Cosmetic Outcome and Quality of Life in Breast Conserving Therapy for Breast Cancer Patients (STARLINGS Study)

An Integrated Optimization of Surgery and Radiotherapy Techniques to Improve Cosmetic Outcome and Quality of Life in Breast Conserving Therapy for Breast Cancer Patients.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 775 (actual)
• Sponsor: Erasmus Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To assess the role of different combinations of (oncoplastic) surgery and radiotherapy techniques as risk factors for moderate to severe fibrosis and for moderate to poor cosmetic outcome.

Detailed description

The primary objectives of this study are to assess the role of different combinations of (oncoplastic) surgery and radiotherapy techniques as risk factors for moderate to severe fibrosis and for moderate to poor cosmetic outcome. Based on these insights predictive models for the development of moderate to severe fibrosis and moderate to poor cosmetic outcome will be developed. Second, the relation between the presence and severity of fibrosis, cosmetic outcome and different QoL domains and symptoms will be assessed.

Conditions

• Breast Fibrosis
• Breast Cancer
• Breast Cancer Female
• Breast Neoplasms
• Breast Carcinoma in Situ
• Breast Carcinoma

Interventions

Type	Name	Description
OTHER	no intervention	At one timepoint patients will get physical examination of the breasts, medical photographs will be taken, and they will fill in five questionnaires about satisfaction of the breasts, quality of life and general health.

Timeline

• Start date: 2022-04-11
• Primary completion: 2024-02-01
• Completion: 2024-09-20
• First posted: 2022-03-02
• Last updated: 2026-04-13

Locations

4 sites across 1 country: Netherlands