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UnknownNCT05262647

18F-FAPI PET in the Diagnosis of Liver Fibrosis

A Prospective Study for Effectiveness of 18F-FAPI PET in the Diagnosis of Liver Fibrosis: Comparison With Liver Biopsy

Status
Unknown
Phase
Study type
Observational
Enrollment
40 (estimated)
Sponsor
The Affiliated Hospital of Qingdao University · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers

Summary

It is an open label observation clinical trial, all participants are chronic liver disease. The investigators deem to make a novel evaluate criteria to hepatic fibrosis. The point of the clinical trial is to evaluate the novel biomaker 18F-FAPI-04 by PET-CT scan in the evaluation of the hepatic fibrosis.

Detailed description

Participants are with clinically confirmed chronic liver disease,including chronic viral hepatitis, autoimmune hepatitis, liver disease after liver transplantation, nonalcoholic fatty liver disease, alcoholic hepatitis, primary biliary cholangitis, primary sclerosing cholangitis and congestive hepatopathy etc. Participants are without liver tumor and other liver disease besides liver fibrosis Participants has no history of malignant tumors Participants agree to performe FAPI PET and liver biopsy

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TEST18F-FAPIPatients with chronic liver disease underwent 18F-FAPI-04 PET/CT and percutaneous liver biopsy.

Timeline

Start date
2021-12-12
Primary completion
2022-12-01
Completion
2022-12-01
First posted
2022-03-02
Last updated
2022-03-02

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05262647. Inclusion in this directory is not an endorsement.