NCT05261009

PENG Block Versus LP Block for THA Postop Pain

PENG Block Versus LP Block for Postoperative Analgesia After Anterior Total Hip

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 154 (actual)
• Sponsor: Wake Forest University Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this randomized, double blinded, prospective study is to compare the postoperative analgesia provided by the PENG block to that provided by the LPB for patients undergoing primary anterior approach THA.

Detailed description

Regional anesthesia procedures represent a common modality for postoperative analgesia after total hip arthroplasty surgeries (THA). The standard practice many years has been the Lumbar Plexus block (LPB), which anesthetizes the L1-L5 lumbar nerve roots1. While the LPB offers analgesia from the associated sensory block, it also blocks motor fibers, leading to lower extremity weakness that could potentially delay the patient's ability to participate in early physical therapy and may thereby delay discharge. In the past several years, newer regional anesthesia block approaches have been described and investigated in an attempt to provide patients with postoperative analgesia while avoiding associated muscle weakness, facilitating earlier physical therapy participation and discharge. One such nerve block is the peri-capsular nerve group (PENG) block, which anesthetizes the articular branches of the femoral, obturator, and accessory obturator nerves providing sensory innervation to the hip joint capsule without consistently causing lower extremity weakness2. Some institutions are utilizing the PENG block to provide postoperative analgesia and facilitate early mobilization. There are currently no prospective studies that directly compare the efficacy of LPB to PENG block for providing postoperative analgesia after THA.

Conditions

• Pain, Postoperative
• Hip Pain Chronic

Interventions

Type	Name	Description
DRUG	Peri-capsular Nerve Group (PENG)	PENG block for postoperative pain management
OTHER	Lumbar Plexus Block (LPB)	LPB for postoperative pain management

Timeline

• Start date: 2022-06-13
• Primary completion: 2023-07-20
• Completion: 2023-07-20
• First posted: 2022-03-02
• Last updated: 2024-05-21
• Results posted: 2024-03-18

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study