Clinical Trials Directory

Trials / Unknown

UnknownNCT05259332

Identification by Transcriptomic Approach of New Prognostic and Predictive Markers in a Cohort of Atypical Meningiomas

Identification by Transcriptomic Approach of New Prognostic and Predictive Markers in a Cohort of Atypical Meningiomas and Immunohistochemical Applications

Status
Unknown
Phase
Study type
Observational
Enrollment
85 (estimated)
Sponsor
Central Hospital, Nancy, France · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Determine by a transcriptomic approach new prognostic and predictive markers in atypical meningiomas (WHO grade II). Retrospective observational study, on a cohort of 85 atypical meningiomas. Transcriptomic study first, on cryopreserved tumor samples. Then identify, thanks to the transcriptomic study, prognostic and predictive factors (study of the link between the quantity of certain RNA transcripts and progression-free survival). Finally, set up immunohistochemical applications, which can be used routinely by the pathologist.

Conditions

Timeline

Start date
2022-02-25
Primary completion
2022-04-01
Completion
2023-10-31
First posted
2022-02-28
Last updated
2022-02-28

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT05259332. Inclusion in this directory is not an endorsement.