NCT05258643

The Role of Natural Killer, Complement and T-lymphocytes in COVID-19 Disease, a Prospective Monocentric Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (estimated)
• Sponsor: Universitair Ziekenhuis Brussel · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The current study is an open, non-randomized, monocentric, and interventional study. CoViD-19 patients will be recruited at UZ Brussel after informed consent is obtained. Whole blood and serum samples will be collected during acute disease (inclusion and 7 days after inclusion) and during patient follow-up at 2 months after infection. Sample storage and subsequent use in fundamental research will be performed at VUB Neuro-Aging and Viro-Immunotherapy. Additionally, medical records of UZ Brussel will be searched and epidemiological, clinical, radiological, and biological data of the selected patients will be obtained at the diagnosis time point and during follow-up. Healthy volunteers will be recruited as well in the current study, as a comparison arm, after informed consent is obtained.

Conditions

• Complement Abnormality
• Peripheral Blood Mononuclear Cells
• Covid19

Interventions

Type	Name	Description
OTHER	Blood analysis	Venipuncture and collection of serum and whole blood

Timeline

• Start date: 2020-09-01
• Primary completion: 2024-05-01
• Completion: 2024-09-01
• First posted: 2022-02-28
• Last updated: 2022-02-28

Locations

1 site across 1 country: Belgium